bpr [2020-04-24 16:19:59]

bacillopeptidase F

Locus: BSU_15300

Isoelectric point: 4.98

Molecular weight: 154.34 kDa

Protein length: 1433 aa

Gene length: 4302 bp

Function: protein degradation

Product: bacillopeptidase F

Essential: no

Synonyms: bpf

Genomic Context

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Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Utilization of nitrogen sources other than amino acids → Utilization of proteins
• Information processing → Protein synthesis, modification and degradation → Proteolysis → Extracellular feeding proteases
• Groups of genes → Secreted proteins

Gene

Coordinates: 1,599,283 → 1,603,584

The protein

Protein family

• peptidase S8 family (according to UniProt)

Domains

• Inhibitor I9 domain (aa 68-177) (according to UniProt)
• Peptidase S8 domain (aa 200-512) (according to UniProt)

Localization

• secreted (according to Swiss-Prot), extracellular (signal peptide) PubMed

Expression and Regulation

Operons

• Genes: bpr
  Description: PubMed

  Regulatory mechanism

  • DegU: activation, DegU-P PubMed, in DegU regulon

  Regulation

  • repressed by glucose (7.7-fold) PubMed

Biological materials

Mutant

• KO7 (ΔnprE ΔaprE Δepr Δmpr ΔnprB Δvpr Δbpr), available as BGSC 1A1133
• BKE15300 (Δbpr::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCATCCCCCTTTTTC, downstream forward: _UP4_TAAGTGGAAAAAAAGCTGCC
• BKK15300 (Δbpr::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCATCCCCCTTTTTC, downstream forward: _UP4_TAAGTGGAAAAAAAGCTGCC

References

Reviews

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Original publications

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